Cancer Risk Gene Found In Donor’s Sperm Used To Conceive Nearly 200 Children Across Europe

Brief by Shorts91 Newsdesk / 12:38pm on 10 Dec 2025,Wednesday Health & Wellness

A major probe has found that a sperm donor carrying a cancer-causing TP53 gene mutation fathered at least 197 children in Europe. Some children have already developed cancer, and a few have died. The donor passed normal checks, but up to 20% of his sperm carried the mutation linked to Li-Fraumeni syndrome, which gives a high lifetime cancer risk. The sperm was used in 14 countries. A small number of British women who travelled abroad for treatment have been informed. Experts say there is no global limit on sperm use and screening cannot catch every risk. (PC: BBC)

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