Moderna And Merck's mRNA Cancer Vaccine Shows Promise in Late-Stage Melanoma Trial

Brief by Shorts91 Newsdesk / 06:28am on 20 Aug 2026,Thursday Health & Wellness

Moderna and Merck's personalised mRNA cancer vaccine has shown promising results in a late-stage trial involving patients with high-risk melanoma. The treatment, called intismeran autogene, was tested with Merck's immunotherapy drug Keytruda after patients underwent surgery.   The Phase 3 trial included 1,137 patients with stage IIB to IV melanoma. The combination met its main goal of improving recurrence-free survival and also reduced the risk of the cancer spreading compared with Keytruda alone.   No new safety concerns were reported. Detailed results are expected at a medical meeting, while the companies prepare to discuss possible regulatory approval. (PC: India Today)

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